Research Articles
Decoding TCM Syndromes: An AI-Driven Exploration of Their Biological Basis and Modern Research Frontiers
This article provides a comprehensive analysis for researchers and pharmaceutical developers on how artificial intelligence (AI) is revolutionizing the scientific understanding of Traditional Chinese Medicine (TCM) syndromes.
From Holism to Precision: Network Target Theory as the AI-Driven Paradigm for Decoding and Innovating Traditional Chinese Medicine
This article provides a comprehensive examination of Network Target Theory, the core framework of TCM network pharmacology, tailored for researchers and drug development professionals.
Integrating Herbgenomics and Systems Biology: A Modern Framework for Traditional Medicine Research and Sustainable Drug Discovery
This article provides a comprehensive framework for researchers and drug development professionals on applying systems biology to modernize traditional medicine.
AI-Powered Drug-Target Interaction Prediction in Herbal Medicine: Methods, Validation, and Future Roadmap
This article provides a comprehensive analysis of artificial intelligence (AI) applications in predicting drug-target interactions for herbal medicines.
Unlocking the Therapeutic Potential of Multi-Target Natural Products: From Systems Pharmacology to Precision Drug Design
This article provides a comprehensive synthesis for researchers and drug development professionals on the paradigm of multi-target natural products (MTNPs).
Cross-Validation Accelerates Discovery: Integrating Genome Mining with Dereplication for Novel Natural Products
This article provides a comprehensive guide for researchers and drug development professionals on the strategic integration of genome mining and dereplication to accelerate the discovery of novel bioactive natural products.
AI-Driven Network Pharmacology: Revolutionizing Natural Product Discovery through Multi-Scale Systems Analysis
This article synthesizes the transformative convergence of artificial intelligence (AI) and network pharmacology (NP) in natural product research, a field critical for researchers and drug development professionals.
Taxonomic Dereplication vs. Structure-Based Design: Choosing the Right Strategy for Modern Drug Discovery
This article provides a comprehensive comparative analysis of two dominant strategies in natural product and drug discovery: taxonomic-focused dereplication and structure-based approaches.
In-Silico Fragmentation Tools Compared: A Guide to Accurate Compound Identification and Structural Annotation
In-silico fragmentation prediction is a cornerstone of modern non-targeted analysis, enabling researchers to annotate unknown chemicals in complex samples.
Beyond Cosine: A Strategic Guide to Evaluating Spectral Similarity Scores for Accurate Compound Identification
This article provides a comprehensive framework for researchers, scientists, and drug development professionals to evaluate and select spectral similarity scoring methods for mass spectrometry-based compound identification.