Research Articles
Crafting Molecular Masterpieces: The Pyrrolidine Puzzle
Explore the synthesis of novel benzoylaminocarbothioyl pyrrolidines through imine-azomethine ylide-1,3-dipolar cycloaddition cascade and their promising biological activities.
Crafting a Cure from the Sea: The Synthetic Quest for (−)-Exiguolide
How chemists are building a potent anticancer molecule, atom by atom, in the laboratory.
The Mirror-Molecule Maker: How Chemists Forge the Backbones of Life-Saving Drugs
Explore how aza-enolate alkylation of lactim ethers enables precise synthesis of chiral molecules for pharmaceutical applications.
Architects of the Invisible: Building Molecular Bicycles with a Green Catalyst
Discover how organocatalysis revolutionizes the synthesis of [3.2.1] bicyclooctanes - complex molecular structures crucial for modern pharmaceuticals.
Nature's Blueprint: How a Rare Molecule Is Revolutionizing Medicine-Making
Discover how tetrafibricin's complex structure is inspiring new chemical synthesis methods for creating life-saving medicines.
Nature's Secret Weapons: How a Radical New Method is Brewing Ancient Plant Medicines
Discover how radical cascade cyclization is revolutionizing the synthesis of furanocoumarins, potent plant-derived medicines used to treat cancer, psoriasis, and more.
Molecular LEGO: How Ring Rearrangements and Zincke Chemistry Are Building Tomorrow's Medicines
Exploring revolutionary synthetic strategies combining cycloaddition, ring-rearrangement metathesis, and Zincke chemistry for constructing complex molecular architectures.
Beyond the Ring: The Light-Powered Revolution in Aniline Synthesis
Discover how photochemical dehydrogenation is transforming aniline synthesis, enabling precise nitrogen group placement under mild conditions with sustainable byproducts.