Research Articles
Nature's Blueprints: The New Chemical Artistry Building Better Medicines
Discover how chemists are rewriting the recipe of life, learning to build nature's most complex molecules with stunning precision for better medicines.
The Deep-Sea Detox: How Ferromanganese Nodules Capture Arsenic and Antimony
Explore how ferromanganese nodules act as natural detoxifiers in the deep ocean, concentrating toxic elements like arsenic and antimony through fascinating geochemical and biological processes.
From Nature to Drug Discovery: The Indole Scaffold as a 'Privileged Structure'
Explore the versatile indole scaffold, a privileged structure in medicinal chemistry that forms the backbone of treatments for cancer, depression, inflammation, and infectious diseases.
Can Flow Chemistry Help Us Be Green? | Sustainable Chemical Manufacturing
Explore how flow chemistry is transforming chemical manufacturing with enhanced safety, reduced waste, and improved efficiency for a greener future.
AI and the Flavor Code: How Machine Learning Decodes Nature's Complex Chemistry
Explore how artificial intelligence is revolutionizing flavonoid research, enabling pattern recognition of complex chemical compounds in foods, wines, and medicines.
The Molecular Bridge Builder: How E. coli's Cyclopropane Synthase Defies Chemical Expectations
Discover how E. coli's cyclopropane fatty acid synthase builds molecular bridges through methyl transfer mechanism revealed by isotope and elemental effects.
Macrocycles: The Tiny Rings Revolutionizing Drug Discovery
How macrocycles are bridging the gap between traditional small-molecule drugs and larger biologic treatments to drug the undruggable.
Fungal Alchemy: How Mucor Species Transform Nature's Chemicals
Explore how Mucor fungi act as sophisticated biofactories, performing intricate chemical modifications for sustainable pharmaceutical production.
The Molecular Matchmakers: How Chemistry Finds the Cures of Tomorrow
Discover how combinatorial, medicinal, and biological chemistry work together to transform drug discovery and develop life-saving medicines.
The Iron Claw: How a Toxic Molecule Was Reforged into a Lifeline
Discover how scientists transformed toxic desferrithiocin into life-saving iron chelators through decades of molecular redesign for treating iron overload conditions.