Research Articles
High-Throughput Natural Products Analysis: Optimizing LC-MS Workflows for Drug Discovery
This article provides a comprehensive guide to Liquid Chromatography-Mass Spectrometry (LC-MS) workflows for high-throughput analysis of natural products (NPs).
Inventa Scoring System: A Strategic Framework for Prioritizing Natural Extracts in Drug Discovery
This article introduces and details the Inventa scoring system, a multi-faceted framework designed to systematically evaluate and prioritize natural extracts for drug development.
Decoding Nature's Molecules: A Modern Guide to HR-ESIMS and NMR for Natural Product Structure Elucidation
This comprehensive guide explores the integrated application of High-Resolution Electrospray Ionization Mass Spectrometry (HR-ESIMS) and Nuclear Magnetic Resonance (NMR) spectroscopy for the definitive structural characterization of natural products.
Modern HPLC and GC Methods for Natural Product Isolation: A Comprehensive Guide for Research and Drug Development
This article provides a comprehensive overview of contemporary High-Performance Liquid Chromatography (HPLC) and Gas Chromatography (GC) techniques essential for the isolation and analysis of natural products.
Mastering HILIC-MS: A Complete Guide to Polar Metabolite Analysis for Biomarker Discovery
This comprehensive guide provides researchers and drug development scientists with a complete framework for implementing Hydrophilic Interaction Liquid Chromatography (HILIC) coupled with Mass Spectrometry (MS) for polar metabolite analysis.
GNPS Molecular Networking: A Comprehensive Guide to Metabolite Identification and Discovery
This article provides a thorough overview of GNPS (Global Natural Products Social Molecular Networking) for metabolite identification, tailored for researchers and drug development professionals.
Choosing the Right Tool: A Comprehensive Guide to GC-MS vs. LC-MS for Natural Product Analysis in Modern Research
This definitive guide compares Gas Chromatography-Mass Spectrometry (GC-MS) and Liquid Chromatography-Mass Spectrometry (LC-MS) for the analysis of natural products.
FTIR vs. UHPLC-HRMS: A Comprehensive Guide for Analytical Method Selection in Modern Research
This article provides a detailed comparative analysis of Fourier Transform Infrared (FTIR) Spectroscopy and Ultra-High Performance Liquid Chromatography-High Resolution Mass Spectrometry (UHPLC-HRMS) for researchers and drug development professionals.
Mastering ECD Calculations: The Definitive Guide to Determining Natural Product Absolute Configuration
This comprehensive guide explores the critical role of Electronic Circular Dichroism (ECD) calculations in the structural elucidation of natural products.
Digital Product Passports for Rare Earth Supply Chains: A Framework for Transparency, Sustainability, and Biomedical Security
This article explores the critical role of Digital Product Passports (DPPs) in revolutionizing rare earth element (REE) supply chains, with specific implications for biomedical research and drug development.